According to the Florida Department of Education, school enrollment dropped in Escambia County by 94 students to 40,292. In the 2007-08 school year, the district enrollment was 41,855.
 The largest losses from the fall of 2016 to the fall of 2017 have been in three elementary schools on the west side: Myrtle Grove -108 , Global Learning -95 and Navy Point -90.
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| Enrollment by Grade | 2017-18 | 2016-17 | |
| PK | 892 | 911 | |
| K | 3,130 | 2,987 | |
| 1 | 3,040 | 3,254 | |
| 2 | 3,104 | 3,272 | |
| 3 | 3,445 | 3,412 | |
| 4 | 3,199 | 3,335 | |
| 5 | 3,303 | 3,197 | |
| 6 | 3,127 | 2,962 | |
| 7 | 2,946 | 2,863 | |
| 8 | 2,757 | 2,818 | |
| 9 | 3,280 | 3,213 | |
| 10 | 2,943 | 2,973 | |
| 11 | 2,723 | 2,706 | |
| 12 | 2,403 | 2,483 | |
| Total | 40,292 | 40,386 | -94 |
| Largest High Schools | |||
| J. M. TATE SENIOR HIGH | 2,177 | ||
| ESCAMBIA HIGH | 1,828 | ||
| WASHINGTON SENIOR HIGH | 1,811 | ||
| Largest Middle Schools | |||
| RANSOM MIDDLE | 1,444 | ||
| JIM C. BAILEY MIDDLE | 1,390 | ||
| FERRY PASS MIDDLE | 1,052 | ||
| Largest Elementary Schools | |||
| BEULAH ELEMENTARY | 976 | ||
| PINE MEADOW ELEMENTARY | 952 | ||
| SCENIC HEIGHTS ELEMENTARY | 918 | ||
| Most Growth | 2017-18 | 2016-17 | |
| SCENIC HEIGHTS ELEMENTARY | 918 | 803 | 115 |
| LINCOLN PARK ELEMENTARY | 192 | 120 | 72 |
| PLEASANT GROVE ELEMENTARY | 682 | 619 | 63 |
| ESCAMBIA HIGH | 1,828 | 1,776 | 52 |
| RANSOM MIDDLE | 1,444 | 1,392 | 52 |
| BRATT ELEMENTARY | 477 | 428 | 49 |
| ERNEST WARD MIDDLE | 483 | 435 | 48 |
| PINE MEADOW ELEMENTARY | 952 | 904 | 48 |
| JIM C. BAILEY MIDDLE | 1,390 | 1,353 | 37 |
| BELLVIEW MIDDLE | 1,033 | 998 | 35 |
| JACKIE HARRIS PREPARATORY | 244 | 209 | 35 |
| Most Loss | 2017-18 | 2016-17 | |
| MYRTLE GROVE ELEMENTARY | 512 | 620 | -108 |
| GLOBAL LEARNING ACADEMY | 645 | 740 | -95 |
| NAVY POINT ELEMENTARY | 463 | 553 | -90 |
| PINE FOREST HIGH | 1,614 | 1,689 | -75 |
| LONGLEAF ELEMENTARY | 655 | 722 | -67 |
| BRENTWOOD ELEMENTARY | 521 | 568 | -47 |
| CORDOVA PARK ELEMENTARY | 658 | 705 | -47 |
| ESCAMBIA WESTGATE CENTER | 177 | 217 | -40 |
| REINHARDT HOLM ELEMENTARY | 415 | 452 | -37 |
| WOODHAM MIDDLE | 744 | 777 | -33 |