FDOH shows the county has 102 cases among residents and staff at local long-term care facilities. The increase of 32 cases since 6 Â p.m. Tuesday is most likely from the specimens taken at Southern Oaks on Monday.
| Rank | County | LTC Cases | Deaths |
| 1 | Dade | 455 | 48 |
| 2 | Broward | 255 | 38 |
| 3 | Palm Beach | 164 | 27 |
| 4 | Manatee | 133 | 14 |
| 5 | Pinellas | 132 | 6 |
| 6 | Clay | 117 | 6 |
| 7 | Escambia | 102 | 7 |
| 8 | Suwanee | 90 | 9 |
| 9 | Leon | 67 | 1 |
| 10 | Polk | 59 | 7 |
In the past 24 hours, Escambia County had a spike of 81 cases (Underhill curse ):
| 4/21/20 | 4/22/20 | |||
| 11 a.m. | 11 a.m. | Increase | ||
| Total Cases | 27495 | 28309 | 814 | 2.96% |
| Florida Residents | 26761 | 27543 | 782 | 2.92% |
| Non-Fla. | 734 | 766 | 32 | 4.36% |
| Deaths | 839 | 893 | 54 | 6.44% |
| Escambia | 337 | 418 | 81 | 24.04% |
| Okaloosa | 134 | 135 | 1 | 0.75% |
| Santa Rosa | 141 | 144 | 3 | 2.13% |
| Broward | 4149 | 4168 | 19 | 0.46% |
| Esc LTC cases | 69 | 102 | 32 | 46.37% |